BREAK THROUGHS START

WITH YOU

Message from the CEO and Chair of the Board

 

When individuals unite under a single purpose, the dreams we share come within reach. Alone, a single donation or volunteer hour is meaningful. When combined they become powerful.

This year, thousands of us worked together:

  • to make 17 groundbreaking research projects possible – from testing treatments in real-world settings to developing insightful research models.
  • to invest in early-career scientists to ensure the longevity of ovarian cancer research.
  • to develop best practices for patient-research engagement so every study delivers lasting impact for those facing this disease.
  • to empower 1,350 Canadians to understand their risk, educate hundreds of clinicians, and mobilize provincial and territorial governments to expand the use of a powerful prevention pathway.
  • to support women facing the disease today with our revamped online discussion forum, OVdialogue, and Teal Teas, uniting those facing ovarian cancer in hope and solidarity.
  • to advocate for more gynecologic oncologists in British Columbia, bringing specialized care closer to home.

Every dollar you donate, every story we tell, every step we take together, turns hope into progress. Thank you for joining forces, demanding action, and building a future where women live freely, fully and uninhibited by this disease.

These breakthroughs started with you.

With gratitude,

Headshot of Tania Vrionis

Tania Vrionis, Chief Executive Officer

Headshot of Karen Greve Young

Karen Greve Young, Chair of the Board

Your Impact

Your fundraising and donations were invested across research, advocacy and support programs, helping us make progress toward eradicating ovarian cancer. You aren’t just funding today’s work; you ensure tomorrow’s discoveries, policy wins and community care stay on course.

  • Research 42%

  • Improve Care 21%

  • Fundraising 22%

  • Administration 13%

  • Marketing and Communications 2%

17

new research projects

This year’s research investments study the disease’s many types while advancing prevention, earlier detection, and finding more effective treatments.

View the research showcase

96

patient engagements

We’re leading a shift in research by including patients at every stage of the research process. Improving life after diagnosis starts with listening to those who live it.

Patient Partners in Research

7

early career scientists

We’re funding the next generation of scientists to nurture innovative thinking and ensure research breakthroughs continue for years to come.

About our research
Thank you to Innovation, Science and Economic Development Canada’s Strategic Science Fund for enabling ovarian cancer research to continue through their contribution to Ovarian Cancer Canada.

*this report covers activities from April 1, 2024 – March 31, 2025.

How Karla Takes Us From “No Options” to Early Detection

Karla sitting in the garden, smiling at the camera

In my family, ovarian cancer has always lived in the back of our minds,” shares Karla Henry, her two grandmothers and two great-aunts succumbing to the disease long before genetic testing was an option. Despite always suspecting that their family had a gene mutation, they didn’t know for sure until 2022, after Karla’s mother was diagnosed with ovarian cancer, “Once we knew of my mom’s gene mutation, my siblings and I all got tested. Turned out that all of us girls were positive for the BRCA 2 mutation.” With this information in hand, Karla was offered annual checks to stay on top of her breast cancer risk – something that ended up being critical, “at only 31 years old, they found breast cancer in my very first mammogram.

Early detection tools for breast cancer save thousands of lives every year, but those facing the possibility of ovarian cancer are left with no options – including Karla: “I was offered annual mammograms and breast ultrasounds, but for ovarian cancer was told ‘there’s nothing we can do to manage your risk. Come back when you’re 40, and we’ll discuss [surgery]’.” Faced with the knowledge that ovarian cancer would likely impact each generation of women in her family, Karla is determined to do more than wait. With her $25 monthly donation to Ovarian Cancer Canada, Karla fuels the research that didn’t exist for the women before her.

This year, both you and Karla supported research to uncover the first effective early detection tests for ovarian cancer.

Thanks to your support, the Ovarian Cancer Relief Foundation’s Dawn Ride, and Innovation, Science and Economic Development Canada’s Strategic Science Fund, we invested in two groundbreaking early detection research projects.

We can always hope for a cure, but early detection is almost the first step toward that,” reflects Karla. We’re working toward the first effective early detection tool for ovarian cancer. This is no longer a dream; it’s progress that you’re making possible. “I may have 15 years before I could get ovarian cancer, but I’m hopeful for how much things could advance before then.”

We can always hope for a cure, but early detection is almost the first step toward that. I may have 15 years before I could get ovarian cancer, but I’m hopeful for how much things could advance before then.

Karla, Previvor


Join Karla and become a monthly donor to power research that moves from discovery to real-world impact.

Your ongoing gift ensures research projects like Dr. Mueller’s and Dr. Neilson’s continue without pause – bringing us closer to the day when ovarian cancer is detected so early that it’s a mild warning instead of a life-changing shock.

France, support volunteer diagnosed with ovarian cancer

France, support volunteer diagnosed with ovarian cancer

Relaunched in January 2025, OVdialogue is a peer-powered online forum

“Dedicated spaces like this mean so much to those facing ovarian cancer,” shares France. “There’s a bond formed when you connect, and it makes all the difference to know you aren’t alone in this rare disease.”

Connect Today

Our Teal Teas unite women diagnosed with ovarian cancer across Canada

“These have had such a profound impact on me,” shares an anonymous attendee. “I’ve been dealing with my diagnosis quietly, but meeting and listening to these amazing women has left me feeling truly seen... my spirits have lifted in ways I cannot fully describe.”

Learn more

We empower women with expert-developed information

We empower women, their families and friends, with expert-developed information. From symptom management to genetic testing, we discuss the ins-and-outs of experiencing ovarian cancer.

Get Expert-Developed Info

While we work toward future breakthroughs, you ensure that women are supported today.

From patient support groups to online resources, everyone affected by this disease –patients, their family, friends and healthcare providers – can find the support and answers they need.

The Next Generation of Ovarian Cancer Researchers

This year, we invested over $750,000 in the work of seven early career researchers, ensuring that ovarian cancer research delivers results for years to come.

From uncovering new knowledge about ovarian cancer to designing tools for earlier detection, these scientists are bringing forward the breakthroughs that women facing this disease deserve. After decades of being overlooked, ovarian cancer research is finally gaining momentum. Thanks to visionaries like Tamara, whose decisions today impact generations to come, we’re building a future free of ovarian cancer.

Legacy gifts like Tamara’s are deeply personal acts of hope and determination – ones that drive real, lasting change.

Tamara Rybkin

Tamara Rybkin, founder of the Rybkin Family fund

Jennifer, Walk of Hope fundraiser diagnosed with ovarian cancer

Jennifer, Walk of Hope fundraiser diagnosed with ovarian cancer

Walk Fundraisers Don't Wait for Change, They Create It

The Ovarian Cancer Canada Walk of Hope is the largest and most powerful event of its kind in Canada.

In 2024, more than 3,500 Canadians walked and fundraised with Jennifer to raise $1.4 million, with $1.5 million raised in 2025.

As the only walk in the country solely dedicated to transforming the lives of those facing ovarian cancer, your fundraising improves the experience women face when diagnosed with this disease and brings us closer to a future in which ovarian cancer is ultimately eradicated.

Improving the Quality of Ovarian Cancer Research

To make up for decades of underfunding and accelerate the pace at which we arrive at breakthroughs, we need to ensure that current ovarian cancer research uses the most effective tools. We invested $300,000 in projects this past year to develop new research models for ovarian cancer.

01

Dr. David Cook's Research on Patient Tumour Cells

A major opportunity in ovarian cancer research lies in the access to and utilization of patient tumour cells. Using these cells, known as patient-derived organoids (PDOs), researchers can better understand ovarian cancer and more efficiently test therapies. In this research project Dr. David Cook and his team will expand the number of PDOs to include rare types, including low-grade serous carcinoma and ovarian clear cell carcinoma.

02

Dr. Mark Carey's Research on an Estrogen Receptor Model

Several ovarian cancer types have unique expressions of hormone receptors, like the estrogen receptor. How these receptors appear has been used as a biomarker to select patients for specific treatments, but we haven’t had effective models to study this in ovarian cancer. In this research project, Dr. Mark Carey will develop a model for estrogen receptor-positive ovarian cancer of different types, that can be used to advance future research and improve prevision medicine.

Prevention: A Bold Step Toward Saving Lives

For a disease with no early detection test, prevention is our most powerful tool to protect women from ovarian cancer today.

That’s why, in 2024, Ovarian Cancer Canada launched our prevention effort, including the creation of a Prevention Task Force and broad public awareness campaign. Thanks to the leadership of the Prevention Task Force and the resources they have developed, the prevention pathway is no longer untapped; it’s being put to good use, helping stop this disease before it starts.

Real Results in Year One

1,350

Canadians understood their risk for ovarian cancer

1,350 Canadians understood their risk for ovarian cancer with our digital tool, empowering them to advocate for their healthcare needs.

Understand your risk

524

waiting room posters and clinical resources

524 waiting room posters and clinical resources sent to health professionals providing direct education on ovarian cancer prevention

Access resources

24,775

doctors, and 1,739 nurses and nurse practitioners

24,775 doctors, and 1,739 nurses and nurse practitioners from 11 provinces/territories received digital access to prevention resources through their government and professional associations

OUR PROGRESS

Early detection lab photo of test tubes

A Roadmap for Risk Reduction

With our Prevention Task Force (a team of leading experts including patients, individuals with a genetic mutation known as “previvors,” gynecologic oncologists, genetic counsellors, family doctors and researchers) we worked to expand use of the Prevention Pathway to prevent ovarian cancer in individuals who are high risk for the disease.

LEARN MORE
Marilyn and her daughter, Sharla

Equipping and Empowering Canadians

Preventing ovarian cancer requires Canadians and their healthcare teams to be aware of what puts people at risk of being diagnosed with the disease. We created expert-developed tools to meet people at the exact moment they need information, whether they’re in a doctor’s office or at home.

Understand your risk
Cailey Crawford speaks at the All Party Cancer Caucus in Ontario.

35 meetings educating key stakeholders

We met with 11 provincial and territorial governments this past year to emphasize their role in optimizing the ovarian cancer prevention pathway. By equipping doctors, nurses and patients with our prevention resources, and addressing existing gaps and barriers in prevention care, provincial and territorial governments across Canada can collectively improve ovarian cancer prevention.

ONTARIO MPPS HEAR CALL FOR ACTION 

Putting Patients at the Heart of Discovery

Because of you, patients aren’t an afterthought – they’re our compass. Together, we’re shifting science toward patient-informed discovery, ensuring every breakthrough starts with lived experience.

As a member of Ovarian Cancer Canada’s Patient Partners in Research, knowing that I can present an Indigenous perspective on ovarian cancer that informs the direction of research feels like an important and often-overlooked perspective in this field.

Tiffany, diagnosed with ovarian cancer, Member of the Métis Nation of Alberta

Lead Scientists Dr. Stephanie Lheureux and Dr. Gary Rodin, University Health Network

Investing $400,000 In Real World Research

You powered our Pragmatic Clinical Trials Competition, with $400,000 used to fund studies that test treatments in real-world settings. Because patients helped design this competition, funded projects will reflect diverse ages, cultures and care contexts, answering Tiffany’s call: “How do we ensure every community benefits?”

PPiR members

Publishing Best Practices For Researcher-Patient Partnerships

Along with our Patient Partners in Research we published a landmark paper in Current Oncology, sharing five best practices for patient-informed research to improve the effectiveness of future research:

  1. Start engagement early
  2. Foster true collaboration
  3. Set clear expectations and communicate often
  4. Report on patient partner impact
  5. Ensure resources match the ask
Helen MacKay and Alicia Tone lead a discussion at the Pragmatic Clinical Trials Workshop

Helping Researchers Partner with Patients

At the Canadian Conference on Ovarian Cancer Research, we piloted Partnered Perspectives – a buddy system pairing nine trainees with PPiR members like Tiffany. By co-attending sessions and debriefing side by side, scientists gained fresh insights and patient partners saw their voices shape new research questions.

Expanding Access to Care: From Treatments to Trained Specialists

Canadians wait more than two years on average to access drugs after they have been approved by Health Canada.

This is almost double the wait time compared to other countries. Reducing these delays is especially critical for ovarian cancer because women don’t have time to lose. That’s why we advocate to close this gap, ensuring every treatment reaches the patients who need it, when they need it. “It feels good to be able to make even a little positive difference,” shares Luda, a woman advocating for change after her own ovarian cancer diagnosis. “Researchers and doctors make the final decisions, but they need to understand more than just the numbers. They need to understand how these decisions affect real people – how it affects our daily lives, our families, our futures.”

KEYTRUDA

After collaborating with CCRAN and bringing the patient perspective to the submission, Canada’s Drug Agency recommended that KEYTRUDA (pembrolizumab) be reimbursed by public drug plans. This drug, used to treat certain ovarian cancer patients that have a high prevalence of microsatellite instability in their tumour, is now one step closer to being available to Canadians with ovarian cancer.

ELAHERE

Currently available in the United States, clinical trials have shown that ELAHERE (mirvetuximab soravtansine)offers significant survival benefits for patients with platinum resistant ovarian cancer. We’re advocating for it to become available to Canadians and shared more than 50 patient and caregiver perspectives with Canada’s Drug Agency and INESSS (drug access agency in Quebec) to achieve this.

MEKINIST

The Formulary Management Expert Committee (FMEC), a Canada’s Drug Agency advisory body, recommended that MEKINIST (trametinib) be reimbursed for the treatment of adult patients with recurrent low-grade serous ovarian cancer after Ovarian Cancer Canada provided the patient perspective. Now provincial and territorial governments will negotiate the price of trametinib.

For the first time in years, women in BC are getting their cancer surgery on time.

Dr. Sarah Finlayson, UBC Division Head of Gynecologic Oncology

13

The number of gynecologic oncologists now available in BC

Improved Specialized Care a Win for British Columbians

Improving care for Canadians diagnosed with ovarian cancer does not only mean more treatments, it also means more gynecologic oncologists across the country.

British Columbia has had significant challenges in their cancer care system for many years, with only eight gynecologic oncologists serving 5.5 million people. Ovarian Cancer Canada joined clinicians and patients in advocating for change, together we succeeded. “Increasing the number of gynecologic oncologists in BC has been a huge success,” shares Dr. Sarah Finlayson, who has been a long-time champion for this change. “For the first time in years, women in BC are getting their cancer surgery on time. Last month, 90% of women in BC had their cancer surgeries within our target timelines, ensuring their timely access to care. Our modelling suggests that we have a sufficient number of gynecologic oncologists to meet the provincial demand for years to come.”

Hanta with her husband Valentino smiling

Hanta with her husband, Valentino