By supporting OCC, you are creating a future where ovarian cancer is preventable, curable, and ultimately eradicated.
OVARIAN CANCER RESEARCH IS A PRIORITY THAT WILL NOT BE IGNORED.
This research showcase serves as a comprehensive archive, highlighting pivotal studies and groundbreaking discoveries. It offers a detailed look into the vast array of research efforts aimed at understanding, diagnosing, treating, and ultimately curing ovarian cancer, documenting the progress and impact of these initiatives on the cancer community and beyond.
12
Pre-clinical
Uncovering novel metabolic regulators of T cell function
Searching for novel strategies for immune therapy
Victoria
Lead Scientist: Sarah Mcphedran, University of Victoria (Supervisor Dr. Julian Lum)
All types TreatmentPre-clinical
Exploring the role of PARG in DNA repair and cancer
PARG inhibitors as an alternative therapy for ovarian cancer
Quebec City
Lead Scientist: Nurgul Atalay, Université Laval (Supervisor Dr. Jean-Yves Masson)
High-grade serous TreatmentResearch capacity
Establishing a national registry of clear cell and mucinous ovarian cancers.
Enabling national research on rare forms of ovarian cancer
National
Lead Scientist: Dr. Mark Carey, UBC; Dr. Melica Brodeur, Jewish General Hospital; Dr. Elizabeth Tremblay, CHUM
MucinousClear cell Detection/diagnosisTreatmentMixed methods
Improving access to opportunistic salpingectomy in Canada: a collaboration with the Ovarian Cancer Observatory
Enabling equitable access to ovarian cancer prevention
Vancouver
Lead Scientist: Dr. Gillian Hanley and Dr. David Huntsman, BC Cancer/UBC
All types PreventionResearch capacity
Nova Scotia Ovarian Cancer Biobank
Enhancing local and national collaborative research
Halifax
Lead Scientist: Dr. Stephanie Scott, Nova Scotia Health Authority
All types Cancer biologyExploring a new therapeutic approach for rare ovarian cancers
- Location
- Montreal
- Lead scientist
- Dr. Anne-Marie Mes-Masson
- Type of ovarian cancer
- Rare types
- Research continuum
- Pre-clinical
- Ovarian cancer continuum
- Treatment
Location
Montreal
Lead scientist
Dr. Anne-Marie Mes-Masson
Type of ovarian cancer
Rare types
Research continuum
Research capacity Discovery research Pre-clinical Clinical trial
Ovarian cancer continuum
Cancer biology Prevention Early detection Treatment Survivorship
Understanding and targeting single-stranded DNA gap-filling mechanisms to improve chemotherapy response
- Location
- Sherbrooke
- Lead scientist
- Dr. Alexandre Maréchal
- Type of ovarian cancer
- All types
- Research continuum
- Pre-clinical
- Ovarian cancer continuum
- Treatment
Location
Sherbrooke
Lead scientist
Dr. Alexandre Maréchal
Type of ovarian cancer
All types
Research continuum
Research capacity Discovery research Pre-clinical Clinical trial
Ovarian cancer continuum
Cancer biology Prevention Early detection Treatment Survivorship
Investigating the “surfaceome” to discover new treatments for rare ovarian cancers
- Location
- Vancouver
- Lead scientist
- Dr. Yemin Wang
- Type of ovarian cancer
- Rare types
- Research continuum
- Pre-clinical
- Ovarian cancer continuum
- Treatment
Location
Vancouver
Lead scientist
Dr. Yemin Wang
Type of ovarian cancer
Rare types
Research continuum
Research capacity Discovery research Pre-clinical Clinical trial
Ovarian cancer continuum
Cancer biology Prevention Early detection Treatment Survivorship
Understanding how glycosylated antitumour ether lipids (GAELs) kill chemotherapy-resistant cancer cells
- Location
- Winnipeg
- Lead scientist
- Sara Crooks (Dr. Mark Nachtigal)
- Type of ovarian cancer
- High-grade serous
- Research continuum
- Pre-clinical
- Ovarian cancer continuum
- Treatment
Location
Winnipeg
Lead scientist
Sara Crooks (Dr. Mark Nachtigal)
Type of ovarian cancer
High-grade serous
Research continuum
Research capacity Discovery research Pre-clinical Clinical trial
Ovarian cancer continuum
Cancer biology Prevention Early detection Treatment Survivorship
Remodeling the immune microenvironment of ovarian cancer using oncolytic viruses
- Location
- Sherbrooke
- Lead scientist
- Zacharie Drouin (Dr. Marilyne Labrie)
- Type of ovarian cancer
- All types
- Research continuum
- Pre-clinical
- Ovarian cancer continuum
- Treatment
Location
Sherbrooke
Lead scientist
Zacharie Drouin (Dr. Marilyne Labrie)
Type of ovarian cancer
All types
Research continuum
Research capacity Discovery research Pre-clinical Clinical trial
Ovarian cancer continuum
Cancer biology Prevention Early detection Treatment Survivorship
Metabolic engineering of CAR-T cells to overcome immune suppression
- Location
- Victoria
- Lead scientist
- Jessica Morgan (Julian Lum)
- Type of ovarian cancer
- High-grade serous
- Research continuum
- Pre-clinical
- Ovarian cancer continuum
- Treatment
Location
Victoria
Lead scientist
Jessica Morgan (Julian Lum)
Type of ovarian cancer
High-grade serous
Research continuum
Research capacity Discovery research Pre-clinical Clinical trial
Ovarian cancer continuum
Cancer biology Prevention Early detection Treatment Survivorship
Metabolic Gene-Edited CAR-T Cells For Ovarian Cancer Treatment
- Location
- Victoria
- Lead scientist
- Dr. Julian Lum
- Type of ovarian cancer
- All types
- Research continuum
- Pre-clinical
- Ovarian cancer continuum
- Treatment
Location
Victoria
Lead scientist
Dr. Julian Lum
Type of ovarian cancer
All types
Research continuum
Research capacity Discovery research Pre-clinical Clinical trial
Ovarian cancer continuum
Cancer biology Prevention Early detection Treatment Survivorship
Optimizing an off-the shelf ovarian cancer RNA vaccine
- Location
- Montreal
- Lead scientist
- Dr. Claude Perreault
- Type of ovarian cancer
- All types
- Research continuum
- Pre-clinical
- Ovarian cancer continuum
- Treatment
Location
Montreal
Lead scientist
Dr. Claude Perreault
Type of ovarian cancer
All types
Research continuum
Research capacity Discovery research Pre-clinical Clinical trial
Ovarian cancer continuum
Cancer biology Prevention Early detection Treatment Survivorship
Fallopian imaging and lavage for early-stage tubo-ovarian cancer detection
- Location
- Vancouver
- Lead scientist
- Dr. Andrea Neilson
- Type of ovarian cancer
- High-grade serous
- Research continuum
- Pre-clinical
- Ovarian cancer continuum
- Early detection
Location
Vancouver
Lead scientist
Dr. Andrea Neilson
Type of ovarian cancer
High-grade serous
Research continuum
Research capacity Discovery research Pre-clinical Clinical trial
Ovarian cancer continuum
Cancer biology Prevention Early detection Treatment Survivorship
The earlier detection of ovarian cancer using an mDETECT liquid biopsy
- Location
- Kingston
- Lead scientist
- Dr. Christopher Mueller
- Type of ovarian cancer
- All types
- Research continuum
- Pre-clinical
- Ovarian cancer continuum
- Early detection
Location
Kingston
Lead scientist
Dr. Christopher Mueller
Type of ovarian cancer
All types
Research continuum
Research capacity Discovery research Pre-clinical Clinical trial
Ovarian cancer continuum
Cancer biology Prevention Early detection Treatment Survivorship
Using patient-derived models and drug sensitivity testing to guide personalized medicine: a proof-of-concept trial
- Location
- Saskatooon
- Lead scientist
- Dr. Laura Hopkins
- Type of ovarian cancer
- All types
- Research continuum
- Clinical trial
- Ovarian cancer continuum
- Treatment
Location
Saskatooon
Lead scientist
Dr. Laura Hopkins
Type of ovarian cancer
All types
Research continuum
Research capacity Discovery research Pre-clinical Clinical trial
Ovarian cancer continuum
Cancer biology Prevention Early detection Treatment Survivorship
ES2 trial: combining a PARP inhibitor and apoptosis sensitizer
- Location
- Montreal
- Lead scientist
- Dr. Diane Provencher
- Type of ovarian cancer
- High-grade serous
- Research continuum
- Clinical trial
- Ovarian cancer continuum
- Treatment
Location
Montreal
Lead scientist
Dr. Diane Provencher
Type of ovarian cancer
High-grade serous
Research continuum
Research capacity Discovery research Pre-clinical Clinical trial
Ovarian cancer continuum
Cancer biology Prevention Early detection Treatment Survivorship
Supercharging CAR-T cells for Ovarian Cancer
- Location
- Victoria
- Lead scientist
- Dr. Brad Nelson
- Type of ovarian cancer
- All types
- Research continuum
- Pre-clinical
- Ovarian cancer continuum
- Treatment
Location
Victoria
Lead scientist
Dr. Brad Nelson
Type of ovarian cancer
All types
Research continuum
Research capacity Discovery research Pre-clinical Clinical trial
Ovarian cancer continuum
Cancer biology Prevention Early detection Treatment Survivorship
Building a scientific toolbox to study low-grade serous ovarian cancer
- Location
- Vancouver
- Lead scientist
- Dr. Mark Carey
- Type of ovarian cancer
- Low-grade serous
- Research continuum
- Research capacity
- Ovarian cancer continuum
- Cancer biology
Location
Vancouver
Lead scientist
Dr. Mark Carey
Type of ovarian cancer
Low-grade serous
Research continuum
Research capacity Discovery research Pre-clinical Clinical trial
Ovarian cancer continuum
Cancer biology Prevention Early detection Treatment Survivorship
Tumour testing and ovarian cancer drug prediction program
- Location
- Saskatoon
- Lead scientist
- Dr. Laura Hopkins
- Type of ovarian cancer
- High-grade serous
- Research continuum
- Clinical trial
- Ovarian cancer continuum
- Treatment
Location
Saskatoon
Lead scientist
Dr. Laura Hopkins
Type of ovarian cancer
High-grade serous
Research continuum
Research capacity Discovery research Pre-clinical Clinical trial
Ovarian cancer continuum
Cancer biology Prevention Early detection Treatment Survivorship
Every Woman Study: Canadian Edition
- Location
- Toronto [pan-Canadian]
- Lead scientist
- Ovarian Cancer Canada
- Type of ovarian cancer
- All types
- Research continuum
- Discovery research
- Ovarian cancer continuum
- Treatment Survivorship
Location
Toronto [pan-Canadian]
Lead scientist
Ovarian Cancer Canada
Type of ovarian cancer
All types
Research continuum
Research capacity Discovery research Pre-clinical Clinical trial
Ovarian cancer continuum
Cancer biology Prevention Early detection Treatment Survivorship
Phase II clinical trial of CX5461 at the time of disease progression on a PARP inhibitor
- Location
- Toronto
- Lead scientist
- Dr. Amit Oza
- Type of ovarian cancer
- High-grade serous
- Research continuum
- Clinical trial
- Ovarian cancer continuum
- Treatment
Location
Toronto
Lead scientist
Dr. Amit Oza
Type of ovarian cancer
High-grade serous
Research continuum
Research capacity Discovery research Pre-clinical Clinical trial
Ovarian cancer continuum
Cancer biology Prevention Early detection Treatment Survivorship
Exploring and exploiting aberrant RBX1 expression in high-grade serous ovarian cancer
- Location
- Winnipeg
- Lead scientist
- Dr. Kirk McManus
- Type of ovarian cancer
- High-grade serous
- Research continuum
- Pre-clinical
- Ovarian cancer continuum
- Cancer biology
Location
Winnipeg
Lead scientist
Dr. Kirk McManus
Type of ovarian cancer
High-grade serous
Research continuum
Research capacity Discovery research Pre-clinical Clinical trial
Ovarian cancer continuum
Cancer biology Prevention Early detection Treatment Survivorship
Understanding the experience of previvors receiving care at a specialized centre
- Location
- Vancouver
- Lead scientist
- Dr. Lesa Dawson
- Type of ovarian cancer
- High-grade serous
- Research continuum
- Discovery research
- Ovarian cancer continuum
- Prevention
Location
Vancouver
Lead scientist
Dr. Lesa Dawson
Type of ovarian cancer
High-grade serous
Research continuum
Research capacity Discovery research Pre-clinical Clinical trial
Ovarian cancer continuum
Cancer biology Prevention Early detection Treatment Survivorship
Targeting epitranscriptomic mechanisms in ovarian cancer
- Location
- Edmonton
- Lead scientist
- Dr. YangXin Fu
- Type of ovarian cancer
- All types
- Research continuum
- Pre-clinical
- Ovarian cancer continuum
- Treatment
Location
Edmonton
Lead scientist
Dr. YangXin Fu
Type of ovarian cancer
All types
Research continuum
Research capacity Discovery research Pre-clinical Clinical trial
Ovarian cancer continuum
Cancer biology Prevention Early detection Treatment Survivorship
CHARM Early Detection Clinical Trial
- Location
- Toronto
- Lead scientist
- Dr. Trevor Pugh
- Type of ovarian cancer
- High-grade serous Endometrioid Clear cell
- Research continuum
- Clinical trial
- Ovarian cancer continuum
- Early detection
Location
Toronto
Lead scientist
Dr. Trevor Pugh
Type of ovarian cancer
High-grade serous Endometrioid Clear cell
Research continuum
Research capacity Discovery research Pre-clinical Clinical trial
Ovarian cancer continuum
Cancer biology Prevention Early detection Treatment Survivorship
NEOCATS trial: Targeting the targets with a combination of three treatments
- Location
- Vancouver
- Lead scientist
- Dr. Yvette Drew
- Type of ovarian cancer
- High-grade serous
- Research continuum
- Clinical trial
- Ovarian cancer continuum
- Treatment
Location
Vancouver
Lead scientist
Dr. Yvette Drew
Type of ovarian cancer
High-grade serous
Research continuum
Research capacity Discovery research Pre-clinical Clinical trial
Ovarian cancer continuum
Cancer biology Prevention Early detection Treatment Survivorship
Developing new treatments for clear cell ovarian cancer
- Location
- Saskatoon
- Lead scientist
- Dr. Franco Vizeacoumar
- Type of ovarian cancer
- Clear cell
- Research continuum
- Pre-clinical
- Ovarian cancer continuum
- Treatment
Location
Saskatoon
Lead scientist
Dr. Franco Vizeacoumar
Type of ovarian cancer
Clear cell
Research continuum
Research capacity Discovery research Pre-clinical Clinical trial
Ovarian cancer continuum
Cancer biology Prevention Early detection Treatment Survivorship
Developing optimal treatment combinations for small cell carcinoma of the ovary
- Location
- Montreal
- Lead scientist
- Dr. Sidong Huang
- Type of ovarian cancer
- Non-epithelial
- Research continuum
- Pre-clinical
- Ovarian cancer continuum
- Treatment
Location
Montreal
Lead scientist
Dr. Sidong Huang
Type of ovarian cancer
Non-epithelial
Research continuum
Research capacity Discovery research Pre-clinical Clinical trial
Ovarian cancer continuum
Cancer biology Prevention Early detection Treatment Survivorship
Development of therapeutic vaccines against ovarian cancer
- Location
- Montreal
- Lead scientist
- Dr. Claude Perreault
- Type of ovarian cancer
- All types
- Research continuum
- Pre-clinical
- Ovarian cancer continuum
- Treatment
Location
Montreal
Lead scientist
Dr. Claude Perreault
Type of ovarian cancer
All types
Research continuum
Research capacity Discovery research Pre-clinical Clinical trial
Ovarian cancer continuum
Cancer biology Prevention Early detection Treatment Survivorship
Re-VOLVE trial: using genomics to make treatment decisions after a PARP inhibitor
- Location
- Toronto
- Lead scientist
- Dr. Stephanie Lheureux
- Type of ovarian cancer
- High-grade serous Endometrioid
- Research continuum
- Clinical trial
- Ovarian cancer continuum
- Treatment
Location
Toronto
Lead scientist
Dr. Stephanie Lheureux
Type of ovarian cancer
High-grade serous Endometrioid
Research continuum
Research capacity Discovery research Pre-clinical Clinical trial
Ovarian cancer continuum
Cancer biology Prevention Early detection Treatment Survivorship
A novel model system to study ovarian cancer/immune cell interactions
- Location
- Halifax
- Lead scientist
- Dr. Jeanette Boudreau
- Type of ovarian cancer
- All types
- Research continuum
- Research capacity
- Ovarian cancer continuum
- Cancer biology
Location
Halifax
Lead scientist
Dr. Jeanette Boudreau
Type of ovarian cancer
All types
Research continuum
Research capacity Discovery research Pre-clinical Clinical trial
Ovarian cancer continuum
Cancer biology Prevention Early detection Treatment Survivorship
Modelling low-grade serous cancer in 3D
- Location
- Vancouver
- Lead scientist
- Dr. Mark Carey
- Type of ovarian cancer
- Low-grade serous
- Research continuum
- Research capacity
- Ovarian cancer continuum
- Cancer biology
Location
Vancouver
Lead scientist
Dr. Mark Carey
Type of ovarian cancer
Low-grade serous
Research continuum
Research capacity Discovery research Pre-clinical Clinical trial
Ovarian cancer continuum
Cancer biology Prevention Early detection Treatment Survivorship